Lung Carcinoma

It frequently talked about the grade of cancer and so this article intends to show the connection between cancer grades, lung carcinoma and differentiated carcinoma. Lung cancer is the leading type of death causing cancer all over the world.
There are various types of lung cancer from which some are more common and others occur rarely. The small cell lung carcinoma is the medical term used to describe lung cancer that arises in the larger airways. It is quite aggressive as it grows rapidly but it is as a less common type of lung cancer. This type of lung carcinoma is however strongly associated to smoking.
Non-small cell lung carcinoma or simply NSCLC is a more frequent type of cancer that affects the lung. The squamous cell lung carcinoma, adenocarcinoma and large cell lung carcinoma are the three subtypes of NSCLC. It is estimated that 1 in 4 patients with lung cancer is diagnosed with squamous cell carcinoma lung cancer.
Lung cancers and all types of cancer receive an indicator called grade. The grade of cancer is established based on how well the cancer cells are differentiated. Depending on the scale that is used, there are currently 3 or 4 grades that cancers are associated with. Grade 1 lung cancer refers to a tumor whose cells are well differentiated, meaning that the cancer cells resemble to the normal cells and cancer is yet not spread and curable. As a particular example, the well differentiated squamous cell carcinoma lung cancers tend to grow more slowly than other types of cancer. Moderately differentiated carcinomas represent a grade 2 cancer and poorly differentiated carcinomas are grade 3 cancers. The latter is the most aggressive type of cancer with worse prognosis. As a general rule, the more the cells are differentiated and are more similar to the normal cells, the better the prognosis and treatment outcome are.
Carcinoma lung cancer is diagnosed on the symptoms, physical examination and several imaging tests. The imaging tests provide important information regarding the location and size of a tumor if it exists. Prior to the imaging tests, laboratory tests may be performed on sputum (matter from the throat and lungs) to rule out bacterial infections or other types of infections. Also, sputum may contain cancer cells in some types of lung carcinoma. If this test does not provide conclusive information in order to establish a diagnosis, chest radiographies, CT scans, MRIs, bronchoscopies, needle biopsies and bone scans may be performed. The bone scan is used to find out if the carcinoma lung cancer has spread to the bones as in metastatic stage.
Prognosis is generally poor for NSCLC with a five year survival rate of 67% which decreases to 1% in patients with stage IV NSCLC. In what concerns small cell lung cancer the prognosis is also unfavorable as the five year survival rate is nearly 5% which gets to less than 1% in patients with metastatic small cell lung cancer.
Lung carcinoma and differentiated carcinoma are two medical terms related by the means of what is called grade of cancer.